Invention Grant
US08815941B2 2,3-fluorinated glycosides as neuraminidase inhibitors and their use as anti-virals
有权
2,3-氟化糖苷作为神经氨酸酶抑制剂及其作为抗病毒剂的用途
- Patent Title: 2,3-fluorinated glycosides as neuraminidase inhibitors and their use as anti-virals
- Patent Title (中): 2,3-氟化糖苷作为神经氨酸酶抑制剂及其作为抗病毒剂的用途
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Application No.: US13382284Application Date: 2010-07-15
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Publication No.: US08815941B2Publication Date: 2014-08-26
- Inventor: Stephen Withers , Andrew Graham Watts , Jin Hyo Kim , Tom Wennekes
- Applicant: Stephen Withers , Andrew Graham Watts , Jin Hyo Kim , Tom Wennekes
- Applicant Address: CA Vancouver
- Assignee: The University of British Columbia
- Current Assignee: The University of British Columbia
- Current Assignee Address: CA Vancouver
- Agency: Bozicevic, Field & Francis LLP
- Agent Carol L. Francis; Rudy J. Ng
- International Application: PCT/CA2010/001063 WO 20100715
- International Announcement: WO2011/006237 WO 20110120
- Main IPC: A61K31/351
- IPC: A61K31/351 ; C07D309/02
Abstract:
Compounds of structural formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza are provided Pharmaceutical preparations thereof and methods for their preparation are also described. The therapeutic effect is achieved via inhibition of viral neuraminidases, also known as viral sialidases. These neuraminidases are classified under the GH34 family of viral enzymes.
Public/Granted literature
- US20120178802A1 2,3-Fluorinated Glycosides as Neuraminidase Inhibitors and Their Use as Anti-Virals Public/Granted day:2012-07-12
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