Invention Grant
- Patent Title: Lipid peptide and hydrogel
- Patent Title (中): 脂质肽和水凝胶
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Application No.: US13685565Application Date: 2012-11-26
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Publication No.: US08816049B2Publication Date: 2014-08-26
- Inventor: Nobuhide Miyachi , Takehisa Iwama , Masahiro Gotoh , Tatsuo Maruyama , Daisuke Koda
- Applicant: Nissan Chemical Industries, Ltd , Kyushu University
- Applicant Address: JP Tokyo JP Fukuoka-Shi
- Assignee: Nissan Chemical Industries, Ltd.,Kyushu University
- Current Assignee: Nissan Chemical Industries, Ltd.,Kyushu University
- Current Assignee Address: JP Tokyo JP Fukuoka-Shi
- Agency: Oliff PLC
- Priority: JP2007-177538 20070705
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K38/08 ; C07K7/06 ; C07K5/107 ; C07K5/103 ; C07K5/11 ; C07K5/117

Abstract:
There is provided a lipid peptide that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A lipid peptide represented by Formula (1): where R1 represents an aliphatic group having 9 to 23 carbon atoms; R2, R3, R4 and R5 independently represent a hydrogen atom, an alkyl group having 1 to 7 carbon atom(s) which optionally has a branched chain having 1 to 3 carbon atom(s), a phenylmethyl group, a phenylethyl group or a —(CH2)n—X group, and at least one of R2, R3, R4 and R5 represents a —(CH2)n—X group; n represents the number of 1 to 4; X represents a guanidino group, a —CONH2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which optionally have 1 to 3 nitrogen atom(s); and m represents 1 or 2, and a hydrogel comprising the lipid peptide.
Public/Granted literature
- US20130144037A1 NOVEL LIPID PEPTIDE AND HYDROGEL Public/Granted day:2013-06-06
Information query
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