Invention Grant
- Patent Title: Triazole derivative as an HSP 90 inhibitor
- Patent Title (中): 三唑衍生物作为HSP90抑制剂
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Application No.: US12523387Application Date: 2007-12-11
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Publication No.: US08816070B2Publication Date: 2014-08-26
- Inventor: Hans Michael Eggenweiler , Michael Wolf , Hans Peter Buchstaller , Christian Sirrenberg
- Applicant: Hans Michael Eggenweiler , Michael Wolf , Hans Peter Buchstaller , Christian Sirrenberg
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE102007002715 20070118
- International Application: PCT/EP2007/010775 WO 20071211
- International Announcement: WO2008/086857 WO 20080724
- Main IPC: A61K31/4196
- IPC: A61K31/4196 ; C07D249/08 ; C07D249/12
Abstract:
5-[4-(2-Methylphenyl)-3-hydroxy-4H-1,2,4-triazol-5-yl]-2,4-dihydroxy-N-methyl-N-butylbenzamide is an HSP90 inhibitor and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.
Public/Granted literature
- US20100113542A1 TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR Public/Granted day:2010-05-06
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