Hydroxybenzamide derivatives and their use as inhibitors of Hsp90

Invention Grant

US08816087B2 Hydroxybenzamide derivatives and their use as inhibitors of Hsp90 有权

Title translation: 羟基苯甲酰胺衍生物及其作为Hsp90抑制剂的用途

Patent Title: Hydroxybenzamide derivatives and their use as inhibitors of Hsp90
Patent Title (中): 羟基苯甲酰胺衍生物及其作为Hsp90抑制剂的用途
Application No.: US11680830

Application Date: 2007-03-01
Publication No.: US08816087B2

Publication Date: 2014-08-26
Inventor: Gianni Chessari , Miles Stuart Congreve , Martyn Frederickson , Christopher William Murray , Eva Figueroa Navarro , Alison Jo-Anne Woolford
Applicant: Gianni Chessari , Miles Stuart Congreve , Martyn Frederickson , Christopher William Murray , Eva Figueroa Navarro , Alison Jo-Anne Woolford
Applicant Address: GB Cambridge
Assignee: Astex Therapeutics Limited
Current Assignee: Astex Therapeutics Limited
Current Assignee Address: GB Cambridge
Agency: Vedder Price P.C.
Agent Thomas J. Kowalski; Deborah L. Lu
Priority: GB0507474.5 20050413; GB0604111.5 20060301
Main IPC: C07D217/00
IPC: C07D217/00 ; A61K31/47

Abstract:

The invention provides compounds of the general formula (I) which have activity as Hsp90 inhibitors.

Abstract(Chinese):

本发明提供具有作为Hsp90抑制剂活性的通式（I）的化合物。

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