Invention Grant
![Crystalline forms of an 8-azabicyclo[3.2.1]octane compound](/docs/US/2014-08-26/US08816091B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline forms of an 8-azabicyclo[3.2.1]octane compound
- Patent Title (中): 8-氮杂双环[3.2.1]辛烷化合物的结晶形式
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Application No.: US13965691Application Date: 2013-08-13
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Publication No.: US08816091B2Publication Date: 2014-08-26
- Inventor: Sean Dalziel , Leticia M. Preza , Miroslav Rapta , Pierre-Jean Colson
- Applicant: Sean Dalziel , Leticia M. Preza , Miroslav Rapta , Pierre-Jean Colson
- Applicant Address: US CA South San Francisco
- Assignee: Theravance Biopharma R&D IP, LLC
- Current Assignee: Theravance Biopharma R&D IP, LLC
- Current Assignee Address: US CA South San Francisco
- Agent Jeffrey A. Hagenah; Roberta P. Saxon
- Main IPC: C07D221/02
- IPC: C07D221/02 ; A61K45/06 ; A61K31/485 ; C07D451/02 ; A61K31/46
![Crystalline forms of an 8-azabicyclo[3.2.1]octane compound](/abs-image/US/2014/08/26/US08816091B2/abs.jpg.150x150.jpg)
Abstract:
The invention provides a crystalline sulfate salt of 3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline salt forms.
Public/Granted literature
- US20140080856A1 CRYSTALLINE FORMS OF AN 8-AZABICYCLO[3.2.1]OCTANE COMPOUND Public/Granted day:2014-03-20
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