Invention Grant
- Patent Title: Stat5b transgenic mice and methods of use thereof
- Patent Title (中): Stat5b转基因小鼠及其使用方法
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Application No.: US13761984Application Date: 2013-02-07
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Publication No.: US08816151B2Publication Date: 2014-08-26
- Inventor: Jin-Xiong She , Bo Chen
- Applicant: Georgia Health Sciences University Research Institute, Inc.
- Applicant Address: US GA Augusta
- Assignee: Georgia Regents Research Institute, Inc.
- Current Assignee: Georgia Regents Research Institute, Inc.
- Current Assignee Address: US GA Augusta
- Agency: Pabst Patent Group LLP
- Main IPC: A01K67/027
- IPC: A01K67/027 ; G01N33/574 ; A61K31/277 ; A61K31/12 ; G01N33/68 ; A61K31/353
Abstract:
It has been discovered that STAT5 phosphorylation and CD150 are effective biomarkers for detecting, diagnosing, and monitoring hematological malignancies, including for example lymphomas. Compositions and methods for identifying therapeutic agents for the treatment of hematologic malignancies using p-STAT5, CD150 or both as biomarkers are described.
Public/Granted literature
- US20130212715A1 Biomarkers for Hematologic Malignacies Public/Granted day:2013-08-15
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