An organic electroluminescence device comprises the following structure: a conductive base (110), a hole injection layer (120), a light emission layer (140), and a cathode layer (170) are laminated in sequence. The material of the hole injection layer (120) comprises a conductive polymer and an azo initiator. A nano-network structure is provided on the connecting surface of the hole injection layer (120) and the light emission layer (140). After being heated to a higher temperature, the azo initiator can be decompounded to release N2, thus the nano-network structure is formed on the surface of the hole injection layer (120). The nano-network structure can efficiently increase the contacting area of the hole injection layer (120) and the adjacent layer. The injection efficiency of the hole is improved. A manufacturing method of the organic electroluminescence device is also provided.