Apparatus, systems, and fabrication methods are provided for biasing amplifier arrangements inside device packages to a target quiescent current. In one embodiment, an amplifier device has an output interface and includes an amplifier arrangement having an amplifier output and impedance matching circuitry coupled between the amplifier output and the output interface. A method for biasing the amplifier arrangement involves measuring or otherwise obtaining a voltage between the amplifier output and the output interface, determining an estimated quiescent current through the amplifier arrangement based on that voltage, and adjusting a bias voltage provided to the input of the amplifier arrangement based on a difference between the estimated quiescent current. In exemplary embodiments, the bias voltage is adjusted until the estimated quiescent current is substantially equal to a target quiescent current.