A mobile device receives RF signals from base stations in a location scanning region. Each of the base stations includes a plurality of distributed transceivers and each distributed transceiver includes an independently configurable antenna array. The mobile device generates and communicates channel measurements for the received radio frequency signals to a remote location server (RLS). The RLS configures, utilizing one or more channel transmit settings, the independently configurable antenna array for the distributed transceivers in the location scanning region, to transmit the RF signals. The RLS determines a coarse position estimate for the mobile device for the sub-regions within the location scanning region and applies different signature functions to the determined coarse position estimate for the sub-regions to generate corresponding sub-regions position estimates. The RLS determines a position estimate for the mobile device based on the sub-regions position estimates and communicates the position estimate to the mobile device.