Invention Grant
- Patent Title: Implant modified with non-hydroxylated vitamin D precursors
- Patent Title (中): 用非羟基化维生素D前体修饰的植入物
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Application No.: US13558971Application Date: 2012-07-26
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Publication No.: US08821568B2Publication Date: 2014-09-02
- Inventor: Ståle Petter Lyngstadaas , Marta Monjo , Christiane Petzold , Jan Erik Ellingsen
- Applicant: Ståle Petter Lyngstadaas , Marta Monjo , Christiane Petzold , Jan Erik Ellingsen
- Applicant Address: ES Palma de Mallorca
- Assignee: Numat Biomedical S.L.
- Current Assignee: Numat Biomedical S.L.
- Current Assignee Address: ES Palma de Mallorca
- Agency: Buchanan Ingersoll & Rooney PC
- Main IPC: A61F2/06
- IPC: A61F2/06

Abstract:
An implant to be used as medical or dental implant, comprising a metallic or polymeric base which is covered by the vitamin D precursor cholecalciferol. The implant can be obtained by direct covering of the polymeric or metallic base with a solution comprising cholecalciferol or also covering the base with the 7-dehydrocholesterol (7-DHC), and subsequently irradiated with UV light to induce the formation of cholecalciferol. Optionally, the coating of the implant may include an antioxidant such as vitamin E. This implant enhances osseointegration in compromised patients by means of the endogenous synthesis and activity of vitamin D in hard and mineralized tissue regeneration. Furthermore, a method to obtain these implants which comprises coating the surface of the implant directly with cholecalciferol or with a specific concentration of 7-DHC and irradiated with UV light to induce the formation of cholecalciferol.
Public/Granted literature
- US20130017234A1 IMPLANT MODIFIED WITH NON-HYDROXYLATED VITAMIN D PRECURSORS Public/Granted day:2013-01-17
Information query
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