Invention Grant
US08821862B2 Soluble β-N-acetylglucosaminidase based antibiofilm compositions and uses thereof
有权
基于N-乙酰氨基葡糖苷酶的抗菌膜组合物及其用途
- Patent Title: Soluble β-N-acetylglucosaminidase based antibiofilm compositions and uses thereof
- Patent Title (中): 基于N-乙酰氨基葡糖苷酶的抗菌膜组合物及其用途
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Application No.: US13416793Application Date: 2012-03-09
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Publication No.: US08821862B2Publication Date: 2014-09-02
- Inventor: Srinivasa Madhyastha , Nanda Yakandawala , Purushottam V. Gawande , Karen Lovetri , Jeffrey B. Kaplan , Daniel Rhoads , Lasha Gogokhia
- Applicant: Srinivasa Madhyastha , Nanda Yakandawala , Purushottam V. Gawande , Karen Lovetri , Jeffrey B. Kaplan , Daniel Rhoads , Lasha Gogokhia
- Applicant Address: CA Winnipeg US NJ New Brunswick
- Assignee: Kane Biotech Inc.,University of Medicine and Dentistry of New Jersey
- Current Assignee: Kane Biotech Inc.,University of Medicine and Dentistry of New Jersey
- Current Assignee Address: CA Winnipeg US NJ New Brunswick
- Agency: Barnes & Thornburg LLP
- Main IPC: A61K38/46
- IPC: A61K38/46 ; A61K38/47
Abstract:
The present invention provides compositions comprising an antibiofilm enzyme, a soluble β-N-acetylglucosaminidase similar to the dspB gene (DispersinB®), and an antimicrobial for preventing growth and proliferation of biofilm-embedded microorganisms in acute and chronic wounds, and methods of treatment. The invention further provides methods for preparing medical devices, and in particular, wound care devices using soluble β-N-acetylglucosaminidase based antimicrobial compositions.
Public/Granted literature
- US20120258089A1 SOLUBLE BETA-N-ACETYLGLUCOSAMINIDASE BASED ANTIBIOFILM COMPOSITIONS AND USES THEREOF Public/Granted day:2012-10-11
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