Invention Grant
US08821883B2 Method of treating B cell cancers by administering truncated BAFF receptors
有权
通过施用截短的BAFF受体来治疗B细胞癌的方法
- Patent Title: Method of treating B cell cancers by administering truncated BAFF receptors
- Patent Title (中): 通过施用截短的BAFF受体来治疗B细胞癌的方法
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Application No.: US13645104Application Date: 2012-10-04
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Publication No.: US08821883B2Publication Date: 2014-09-02
- Inventor: Christine Ambrose , Jeffrey Thompson , Yen-Ming Hsu , Dingyi Wen , Yaping Sun
- Applicant: Biogen Idec MA Inc.
- Applicant Address: US MA Cambridge
- Assignee: Biogen Idec MA Inc.
- Current Assignee: Biogen Idec MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP.
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/17 ; A61K38/18 ; C07K14/435 ; C07K14/705 ; C07K14/71 ; C07K14/715
Abstract:
The disclosure provides a non-naturally occurring BAFF-R glycoprotein having a deletion in the extracellular domain which results in an altered O-linked glycosylation pattern. The disclosure also provides methods and pharmaceutical compositions for treating B-cell- and T-cell-mediated disorders.
Public/Granted literature
- US20130177558A1 Method of Treating Immunological Disorders by Administering Truncated BAFF Receptors Public/Granted day:2013-07-11
Information query
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