Invention Grant
- Patent Title: Live attenuated rotavirus vaccine for oral administration
- Patent Title (中): 用于口服给药的活减毒轮状病毒疫苗
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Application No.: US13486039Application Date: 2012-06-01
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Publication No.: US08821891B2Publication Date: 2014-09-02
- Inventor: Vincent Vande Velde
- Applicant: Vincent Vande Velde
- Applicant Address: BE Rixensart
- Assignee: GlaxoSmithKline Biologicals sa
- Current Assignee: GlaxoSmithKline Biologicals sa
- Current Assignee Address: BE Rixensart
- Agent Haiyan Chen; James C Kellerman; Carl W. Battle
- Priority: GB0503337.8 20050217
- Main IPC: C12N7/00
- IPC: C12N7/00
Abstract:
The invention provides liquid rotavirus formulations that are suitable for oral administration to human infants. In particular the invention provides pharmaceutical compositions and vaccines, comprising a rotavirus antigen, a sugar and a carboxylate wherein said formulation has a pH of between pH 5.0 and pH 8.0 and comprises no phosphate or less than 5 mM phosphate. The invention also provides methods of preparing said rotavirus formulations and use thereof in the prevention or treatment of rotavirus associated diseases in humans.
Public/Granted literature
- US20120237547A1 LIVE ATTENUATED ROTAVIRUS VACCINE FOR ORAL ADMINISTRATION Public/Granted day:2012-09-20
Information query
