Invention Grant
- Patent Title: Method for optimizing a biopharmaceutical production process
- Patent Title (中): 优化生物制药生产过程的方法
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Application No.: US13514692Application Date: 2010-12-17
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Publication No.: US08822198B2Publication Date: 2014-09-02
- Inventor: Stefan Schlatter , Christian Sauter , Eugen Probst , Franz Wiedemann , Carina Guelch
- Applicant: Stefan Schlatter , Christian Sauter , Eugen Probst , Franz Wiedemann , Carina Guelch
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Alan R. Stempel
- Priority: EP09179954 20091218; EP10161272 20100428
- International Application: PCT/EP2010/070042 WO 20101217
- International Announcement: WO2011/073377 WO 20110623
- Main IPC: C12N1/00
- IPC: C12N1/00 ; C12N5/02
Abstract:
The invention describes the development of a new buffer system for cell culture media for establishing a CO2 regulation in the bioreactor with eukaryotic cells. This technology makes it possible to obtain CO2 regulation for process control, process optimization and scaling. In addition, the invention describes a specific cell culture medium with specific buffer substances.
Public/Granted literature
- US20130244275A1 METHOD FOR OPTIMIZING A BIOPHARMACEUTICAL PRODUCTION PROCESS Public/Granted day:2013-09-19
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