Invention Grant
US08822218B2 Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
有权
从人胚胎干细胞衍生的成血成血管细胞产生天然杀伤细胞和树突状细胞的方法
- Patent Title: Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
- Patent Title (中): 从人胚胎干细胞衍生的成血成血管细胞产生天然杀伤细胞和树突状细胞的方法
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Application No.: US13512795Application Date: 2010-12-01
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Publication No.: US08822218B2Publication Date: 2014-09-02
- Inventor: Erin Kimbrel , Shi-Jiang Lu
- Applicant: Erin Kimbrel , Shi-Jiang Lu
- Applicant Address: US CA Los Angeles
- Assignee: Stem Cell & Regenerative Medicine International, Inc.
- Current Assignee: Stem Cell & Regenerative Medicine International, Inc.
- Current Assignee Address: US CA Los Angeles
- Agency: Nixon Peabody, LLP
- Agent Seth D. Levy
- International Application: PCT/US2010/058593 WO 20101201
- International Announcement: WO2011/068896 WO 20110609
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02
Abstract:
This invention provides methods of generating natural killer (NK) cells and dendritic cells (DCs). The methods utilize human hemangioblasts as intermediate cells to generate the NK cells and DCs. In various embodiments, the methods do not require the use of stromal feeder layers.
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