Invention Grant
US08822407B2 Preparation of conjugates comprising adenine derivatives and allergenic proteins and their use for specific immunotherapy of allengenic diseases
有权
包含腺嘌呤衍生物和过敏性蛋白质的缀合物的制备及其对全身疾病的特异性免疫治疗的用途
- Patent Title: Preparation of conjugates comprising adenine derivatives and allergenic proteins and their use for specific immunotherapy of allengenic diseases
- Patent Title (中): 包含腺嘌呤衍生物和过敏性蛋白质的缀合物的制备及其对全身疾病的特异性免疫治疗的用途
-
Application No.: US13814370Application Date: 2011-08-04
-
Publication No.: US08822407B2Publication Date: 2014-09-02
- Inventor: Sergio Romagnani , Enrico Maggi , Paola Parronchi , Antonio Guarna , Ernesto Giovanni Occhiato
- Applicant: Sergio Romagnani , Enrico Maggi , Paola Parronchi , Antonio Guarna , Ernesto Giovanni Occhiato
- Applicant Address: IT Florence
- Assignee: Universita' Degli Studi di Firenze
- Current Assignee: Universita' Degli Studi di Firenze
- Current Assignee Address: IT Florence
- Agency: Abelman, Frayne & Schwab
- Priority: ITFI2010A0171 20100805
- International Application: PCT/IB2011/053482 WO 20110804
- International Announcement: WO2012/017408 WO 20120209
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present invention refers to the preparation of adenine derivative active esters of formula (I) and use thereof for the preparation of stable conjugates between adenine derivative and allergenic proteins having general structure (II) for the modulation of TH2 response in allergic diseases. (I, II).
Public/Granted literature
Information query
IPC分类:
