Invention Grant
- Patent Title: Dosage of oligonucleotides suitable for the treatment of tumors
- Patent Title (中): 适用于治疗肿瘤的寡核苷酸的剂量
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Application No.: US12453487Application Date: 2009-05-12
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Publication No.: US08822425B2Publication Date: 2014-09-02
- Inventor: Karl-Hermann Schlingensiepen , Hubert Heinrichs , Susanne Schmaus
- Applicant: Karl-Hermann Schlingensiepen , Hubert Heinrichs , Susanne Schmaus
- Applicant Address: DE Regensburg
- Assignee: Antisense Pharma GmbH
- Current Assignee: Antisense Pharma GmbH
- Current Assignee Address: DE Regensburg
- Agency: Jacobson Holman, PLLC.
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07H21/04
Abstract:
A method for preventing and/or treating a tumor, the method comprising: intravenously administering an antisense oligonucleotide in an amount of between about 400 to about 800 mg/m2/treatment cycle, the antisense oligonucleotide comprises 8 to 30 nucleotide building blocks, which hybridizes with mRNA of TGF-beta-2, -1 and/or -3 for the preparation of a pharmaceutical composition.
Public/Granted literature
- US20100286236A1 Dosage of oligonucleotides suitable for the treatment of tumors Public/Granted day:2010-11-11
Information query
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