Invention Grant
- Patent Title: Indazole compounds useful as ketohexokinase inhibitors
- Patent Title (中): 可用作酮基己糖激酶抑制剂的吲唑化合物
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Application No.: US13091344Application Date: 2011-04-21
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Publication No.: US08822447B2Publication Date: 2014-09-02
- Inventor: Xuqing Zhang , Marta C. Abad , Alan C. Gibbs , Gee-Hong Kuo , Lawrence C. Kuo , Fengbin Song , Zhihua Sui
- Applicant: Xuqing Zhang , Marta C. Abad , Alan C. Gibbs , Gee-Hong Kuo , Lawrence C. Kuo , Fengbin Song , Zhihua Sui
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Agent Mary A. Appollina
- Main IPC: A61K31/416
- IPC: A61K31/416 ; A61K31/4439 ; A61K31/454 ; A61K31/4545 ; A61K31/496 ; A61K31/519 ; A61K31/551 ; C07D401/12 ; C07D401/14 ; C07D403/10 ; C07D403/12 ; C07D471/04 ; C07D487/04 ; C07D487/08 ; A61P3/04 ; A61P3/06 ; A61P3/10
Abstract:
The present invention is directed to substituted indazole compounds of formula (I) pharmaceutical compositions of these compounds and methods of use thereof. The compounds of the present invention are ketohexokinase (KHK) inhibitors, useful for treating or ameliorating a KHK mediated metabolic disorders and/or diseases such as obesity, Type II diabetes mellitus and Metabolic Syndrome X.
Public/Granted literature
- US20110263559A1 INDAZOLE COMPOUNDS USEFUL AS KETOHEXOKINASE INHIBITORS Public/Granted day:2011-10-27
Information query
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