Invention Grant
US08822465B2 Quinoline compound composing 1,2,4-triazine-dione and use thereof
有权
组合1,2,4-三嗪 - 二酮的喹啉化合物及其用途
- Patent Title: Quinoline compound composing 1,2,4-triazine-dione and use thereof
- Patent Title (中): 组合1,2,4-三嗪 - 二酮的喹啉化合物及其用途
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Application No.: US13828615Application Date: 2013-03-14
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Publication No.: US08822465B2Publication Date: 2014-09-02
- Inventor: Hua Xu
- Applicant: Hua Xu
- Applicant Address: CN Wuchang District, Wuhan
- Assignee: Wuhan Shengyun Biopharma Co., Ltd.
- Current Assignee: Wuhan Shengyun Biopharma Co., Ltd.
- Current Assignee Address: CN Wuchang District, Wuhan
- Agency: Morris, Manning & Martin, LLP
- Agent Juan Carlos A. Marquez
- Priority: CN201210080827 20120326
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/53 ; C07D401/14 ; C07D401/12
Abstract:
The present invention relates to a quinoline derivative represented by general formula (I) or a pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof, wherein Ar, R1, R2, R3, X, Y and n have the meanings given in the description. The present invention also relates to the comparatively strong effect of the compound represented by general formula (I) on inhibiting c-Met kinase. The present invention further relates to the use of this compound or a pharmaceutically acceptable salt, hydrate, solvate or prodrug thereof in the manufacturing of a medicament for treating the disease caused by abnormally over-expressing c-Met kinase, in particular, for treating or preventing cancer.
Public/Granted literature
- US20130252958A1 QUINOLINE COMPOUND COMPOSING 1,2,4-TRIAZINE-DIONE AND USE THEREOF Public/Granted day:2013-09-26
Information query
IPC分类:
