Invention Grant
- Patent Title: Substituted pyrido[2,3-b]pyrazines
- Patent Title (中): 取代的吡啶并[2,3-b]吡嗪
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Application No.: US13889585Application Date: 2013-05-08
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Publication No.: US08822470B2Publication Date: 2014-09-02
- Inventor: Anthony R. Gangloff , Andrew John Jennings , Benjamin Jones , Andre A. Kiryanov
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agent Matthew J. Russo; Mitchell R. Brustein
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D471/04
![Substituted pyrido[2,3-b]pyrazines](/abs-image/US/2014/09/02/US08822470B2/abs.jpg.150x150.jpg)
Abstract:
Disclosed are compounds of the following formula: in which R1, R2, R3, R4, R5, R6, R7, and X, are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.
Public/Granted literature
- US20130274239A1 POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS Public/Granted day:2013-10-17
Information query
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