Invention Grant
US08822491B2 Methods and compositions for treating β-thalassemia and sickle cell disease
有权
用于治疗地中海贫血和镰状细胞病的方法和组合物
- Patent Title: Methods and compositions for treating β-thalassemia and sickle cell disease
- Patent Title (中): 用于治疗地中海贫血和镰状细胞病的方法和组合物
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Application No.: US13984687Application Date: 2012-01-03
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Publication No.: US08822491B2Publication Date: 2014-09-02
- Inventor: Che-kun James Shen , Yu-Chi Chou
- Applicant: Che-kun James Shen , Yu-Chi Chou
- Applicant Address: TW Taipei
- Assignee: Academia Sinica
- Current Assignee: Academia Sinica
- Current Assignee Address: TW Taipei
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2012/020059 WO 20120103
- International Announcement: WO2012/112232 WO 20120823
- Main IPC: A61K31/4745
- IPC: A61K31/4745 ; A61K31/4738
Abstract:
The present invention provides compounds (such as compounds of formula I-a) that induce γ globin expression and pharmaceutical compositions thereof. Such compounds may have beneficial therapeutic effects. Compounds and compositions described herein may be used to treat hemoglobinopathies such as β-thalassemia and sickle cell anemia.
Public/Granted literature
- US20140088133A1 METHODS AND COMPOSITIONS FOR TREATING BETA-THALASSEMIA AND SICKLE CELL DISEASE Public/Granted day:2014-03-27
Information query
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