Invention Grant
US08822519B2 Compound with agitation effect on peroxisome proliferator-activated receptor process for its preparation and use thereof
有权
具有搅拌作用的过氧化物酶体增殖物激活受体过程的化合物及其制备及其应用
- Patent Title: Compound with agitation effect on peroxisome proliferator-activated receptor process for its preparation and use thereof
- Patent Title (中): 具有搅拌作用的过氧化物酶体增殖物激活受体过程的化合物及其制备及其应用
-
Application No.: US13057737Application Date: 2009-08-07
-
Publication No.: US08822519B2Publication Date: 2014-09-02
- Inventor: Chunhua Jin , Xiaoyu Liu , Zhenliang Chen , Xiaohe Zheng , Shoufeng Ming
- Applicant: Chunhua Jin , Xiaoyu Liu , Zhenliang Chen , Xiaohe Zheng , Shoufeng Ming
- Applicant Address: CN Zhejiang
- Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
- Current Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Zhejiang
- Agency: Knobbe, Martens, Olson & Bear LLP
- Priority: CN200810147310 20080807
- International Application: PCT/CN2009/073140 WO 20090807
- International Announcement: WO2010/015212 WO 20100211
- Main IPC: C07D249/12
- IPC: C07D249/12 ; A61K31/4196 ; A61P3/00 ; A61P3/04 ; A61P3/06 ; A61P3/10 ; A61P25/28 ; A61P5/48 ; A61P35/00

Abstract:
The present invention provides a novel compound of formula I, which has an agitation effect on the peroxisome proliferator-activated receptor subtype δ (PPARδ), to a pharmaceutical composition comprising the compound, to a process for preparation of the compound and to use of the compound in the manufacture of a medicament for treating or preventing a disease which could be treated or prevented by activating PPARδ thereof, said disease is one or more from the group comprising metabolic syndrome, obesity, dyslipidemia, pathoglycemia, insulin resistance, senile dementia and tumors. The present invention also relates to a new intermediate used in the preparation of the novel compound and a process for preparation of the intermediate.
Public/Granted literature
Information query