Invention Grant
US08822542B2 Isoketal scavengers and mitigation of disorders involving oxidative injury
有权
异丙酮清除剂和减轻涉及氧化损伤的疾病
- Patent Title: Isoketal scavengers and mitigation of disorders involving oxidative injury
- Patent Title (中): 异丙酮清除剂和减轻涉及氧化损伤的疾病
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Application No.: US12395464Application Date: 2009-02-27
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Publication No.: US08822542B2Publication Date: 2014-09-02
- Inventor: L. Jackson Roberts, II , Jeffrey R. Balser , Sean S. Davies , Venkataraman Amarnath , Prakash C. Viswanathan
- Applicant: L. Jackson Roberts, II , Jeffrey R. Balser , Sean S. Davies , Venkataraman Amarnath , Prakash C. Viswanathan
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- Agency: Stites & Harbison PLLC
- Agent Richard S. Myers, Jr.
- Main IPC: A01N33/02
- IPC: A01N33/02 ; A61K31/13
Abstract:
A method of treating and/or preventing oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or pyridoxamine or pyridoxamine analog, including embodiments where the phenolic compound is at least one of a pyridoxamine, salicylamine, tyrosine compound or an analog thereof.
Public/Granted literature
- US20120157501A1 ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY Public/Granted day:2012-06-21
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