Invention Grant
- Patent Title: Peptides for activation and inhibition of δPKC
- Patent Title (中): 用于激活和抑制δPKC的肽
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Application No.: US12956900Application Date: 2010-11-30
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Publication No.: US08822636B2Publication Date: 2014-09-02
- Inventor: Daria Mochly-Rosen , Leon E. Chen
- Applicant: Daria Mochly-Rosen , Leon E. Chen
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of The Leland Stanford Junior University
- Current Assignee: The Board of Trustees of The Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: McDermott Will & Emery LLP
- Main IPC: C07K4/00
- IPC: C07K4/00 ; C07K5/103 ; C12N9/12 ; A61K38/00
Abstract:
Peptides able to inhibit or activate the translocation or function of δPKC are identified. Administration of the peptides for protection or enhancement of cell damage due to ischemia is described. Therapeutic methods to reduce damage to cells or to enhance damage to cells due to ischemia are also described, as well as methods for screening test compounds for δPKC-selective agonists and antagonists.
Public/Granted literature
- US20110143991A1 Peptides for Activation and Inhibition of Delta-PKC Public/Granted day:2011-06-16
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