Invention Grant
US08822654B2 Mutated antithrombins, a process for preparing the same and their use as drugs
有权
突变抗血栓素，其制备方法及其作为药物的用途
- Patent Title: Mutated antithrombins, a process for preparing the same and their use as drugs
- Patent Title (中): 突变抗血栓素，其制备方法及其作为药物的用途
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Application No.: US13144995Application Date: 2010-01-15
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Publication No.: US08822654B2Publication Date: 2014-09-02
- Inventor: Delphine Borgel , Véronique Ferger , Elsa Bianchini , Nicolas Lerolle , Jean-Luc René Diehl
- Applicant: Delphine Borgel , Véronique Ferger , Elsa Bianchini , Nicolas Lerolle , Jean-Luc René Diehl
- Applicant Address: FR Orsay FR Paris FR Paris
- Assignee: Universite Paris—Sud XI,Assistance Publique-Hopitaux de Paris,Universite Paris Descartes
- Current Assignee: Universite Paris—Sud XI,Assistance Publique-Hopitaux de Paris,Universite Paris Descartes
- Current Assignee Address: FR Orsay FR Paris FR Paris
- Agency: Young & Thompson
- Priority: EP09290037 20090116
- International Application: PCT/EP2010/050456 WO 20100115
- International Announcement: WO2010/081878 WO 20100722
- Main IPC: A61K35/14
- IPC: A61K35/14 ; C07K1/00 ; C07K14/00 ; C07K16/00 ; C07K17/00 ; A61K38/00 ; A61P5/00 ; A61K38/26 ; A61P7/02 ; C07K14/475 ; A61K38/57 ; C07K14/81 ; C07K14/745 ; A61K38/16 ; C07H21/04 ; A61K38/36
Abstract:
The present invention relates to the use of a composition including of at least a mutated antithrombin having an anticoagulant activity substantially reduced with respect to the anticoagulant activity of the non mutated antithrombin, or having no anticoagulant activity, for the preparation of a drug intended for the prevention or the treatment of pathologies associated with cellular injury, such as infection, inflammation or hypoxic injury.
Public/Granted literature
- US20120088715A1 MUTATED ANTITHROMBINS, A PROCESS FOR PREPARING THE SAME AND THEIR USE AS DRUGS Public/Granted day:2012-04-12
Information query
IPC分类:
