Invention Grant
- Patent Title: Engineered nucleic acids and methods of use thereof
- Patent Title (中): 工程核酸及其使用方法
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Application No.: US13204609Application Date: 2011-08-05
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Publication No.: US08822663B2Publication Date: 2014-09-02
- Inventor: Jason P. Schrum , Stéphane Bancel , Noubar B. Afeyan
- Applicant: Jason P. Schrum , Stéphane Bancel , Noubar B. Afeyan
- Applicant Address: US MA Cambridge
- Assignee: Moderna Therapeutics, Inc.
- Current Assignee: Moderna Therapeutics, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: DT Ward, PC
- Agent Donna T. Ward; Jennifer F. Bryan
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/63 ; A61K31/70
Abstract:
Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful to treat or prevent diseases, disorders or conditions, or to improve a subject's heath or wellbeing.
Public/Granted literature
- US20120065252A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF Public/Granted day:2012-03-15
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