Invention Grant
![Imidazo[1,2-a]pyridine derivative](/docs/US/2014-09-02/US08822688B2/abs.jpg.600x600.jpg)
- Patent Title: Imidazo[1,2-a]pyridine derivative
- Patent Title (中): 咪唑并[1,2-a]吡啶衍生物
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Application No.: US13661601Application Date: 2012-10-26
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Publication No.: US08822688B2Publication Date: 2014-09-02
- Inventor: Kiyohiro Samizu , Naoyuki Masuda , Kazuhiko Iikubo , Yohei Koganemaru , Noriyuki Kawano , Junya Ohmori , Yasuyuki Mitani , Keni Ni
- Applicant: Astellas Pharma Inc.
- Applicant Address: JP Chuo-ku
- Assignee: Astellas Pharma Inc.
- Current Assignee: Astellas Pharma Inc.
- Current Assignee Address: JP Chuo-ku
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2010-101557 20100427
- Main IPC: C07D471/00
- IPC: C07D471/00 ; C07D491/00 ; C07D498/00 ; C07D513/00 ; C07D515/00 ; C07D487/00 ; C07D221/18 ; C07D221/22 ; C07D519/00 ; C07D471/04 ; C07D495/14
![Imidazo[1,2-a]pyridine derivative](/abs-image/US/2014/09/02/US08822688B2/abs.jpg.150x150.jpg)
Abstract:
[Problem]To provide a compound useful as medicine having PDE4B inhibitory activity, in particular, as an active ingredient of a composition for treating or preventing schizophrenia, Alzheimer's disease, dementia, depression and the like.[Measures for Solution]The present inventors examined compounds having PDE4B inhibitory activity and found that a tricyclic or tetracyclic imidazo[1,2-a]pyridine derivative or salts thereof had a superior PDE4B inhibitory activity, thereby completing the present invention. The imidazo[1,2-a]pyridine derivative can be used as an agent for treating or preventing schizophrenia, Alzheimer's disease, dementia, depression and the like.
Public/Granted literature
- US20130053363A1 IMIDAZO[1,2-a]PYRIDINE DERIVATIVE Public/Granted day:2013-02-28
Information query
