Invention Grant
- Patent Title: Process for producing pyrrole compound
- Patent Title (中): 制备吡咯化合物的方法
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Application No.: US13203441Application Date: 2010-02-24
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Publication No.: US08822694B2Publication Date: 2014-09-02
- Inventor: Tomomi Ikemoto , Misayo Sera , Naohiro Fukuda
- Applicant: Tomomi Ikemoto , Misayo Sera , Naohiro Fukuda
- Applicant Address: JP Osaka-shi
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka-shi
- Agency: Edwards Wildman Palmer LLP
- Agent David G. Conlin; Lisa Swiszcz Hazzard
- Priority: JP2009-042975 20090225
- International Application: PCT/JP2010/052874 WO 20100224
- International Announcement: WO2010/098351 WO 20100902
- Main IPC: C07D401/12
- IPC: C07D401/12

Abstract:
The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.
Public/Granted literature
- US20110306769A1 PROCESS FOR PRODUCING PYRROLE COMPOUND Public/Granted day:2011-12-15
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