Provided are a computer program product, system, and method for populating strides of tracks to demote from a first cache to a second cache. A first cache maintains modified and unmodified tracks from a storage system subject to Input/Output (I/O) requests. A determination is made to demote tracks from the first cache. A determination is made as to whether there are enough tracks ready to demote to form a stride, wherein tracks are written to a second cache in strides defined for a Redundant Array of Independent Disk (RAID) configuration. A stride is populated with tracks ready to demote in response to determining that there are enough tracks ready to demote to form the stride. The stride of tracks, to demote from the first cache, are promoted to the second cache. The tracks in the second cache that are modified are destaged to the storage system.