A system includes an engine configured to operate in a first operating state and a second operating state, a particulate filter configured to receive exhaust gas from the engine and filter particulate matter from the exhaust gas, and an oxidation catalyst configured to generate heat to increase a temperature of the exhaust gas during a regeneration process. A sensor is configured to measure an actual temperature of the exhaust gas during the regeneration process. A controller is configured to define a fuel conversion factor based, at least in part, on the actual temperature and an expected temperature of the exhaust gas. The controller is further configured to analyze the fuel conversion factor over time relative to at least one of the first and second operating states of the engine and diagnose a fault in the regeneration process based, at least in part, on the fuel conversion factor.