Invention Grant
US08826904B2 Formulations of aminoglycoside and fosfomycin combinations and methods and systems for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis
有权
氨基糖苷和磷霉素组合的制剂以及治疗呼吸机相关肺炎（VAP）和呼吸机相关气管（VAT）支气管炎的方法和系统
- Patent Title: Formulations of aminoglycoside and fosfomycin combinations and methods and systems for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis
- Patent Title (中): 氨基糖苷和磷霉素组合的制剂以及治疗呼吸机相关肺炎（VAP）和呼吸机相关气管（VAT）支气管炎的方法和系统
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Application No.: US13844244Application Date: 2013-03-15
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Publication No.: US08826904B2Publication Date: 2014-09-09
- Inventor: Alan Bruce Montgomery
- Applicant: Cardeas Pharma Inc.
- Applicant Address: US WA Seattle
- Assignee: Cardeas Pharma Corporation
- Current Assignee: Cardeas Pharma Corporation
- Current Assignee Address: US WA Seattle
- Agency: Orrick, Herrington & Sutcliffe LLP
- Main IPC: A61K31/7036
- IPC: A61K31/7036 ; A61M16/00 ; A61M16/16 ; A61K31/665 ; A61K9/12
Abstract:
The present invention is antibiotic compositions, ventilator based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an in-line nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
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