Invention Grant
- Patent Title: Method to enhance an immune response of nucleic acid vaccination
- Patent Title (中): 增强核酸疫苗免疫应答的方法
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Application No.: US13292778Application Date: 2011-11-09
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Publication No.: US08828405B2Publication Date: 2014-09-09
- Inventor: Andrew David Bacon , Peter Laing , Gregory Gregoriadis , Wilson Romero Caparros-Wanderley
- Applicant: Andrew David Bacon , Peter Laing , Gregory Gregoriadis , Wilson Romero Caparros-Wanderley
- Applicant Address: GB London
- Assignee: Lipoxen Technologies Limited
- Current Assignee: Lipoxen Technologies Limited
- Current Assignee Address: GB London
- Agency: One3 IP Management, PC
- Agent Dean G. Stathakis; Peter D. Weinstein
- Priority: EP02254733 20020705
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/12 ; A61K39/02 ; A61K9/127 ; A61K39/145 ; C12N7/00
Abstract:
A composition comprising liposomes associated with a nucleic acid operatively encoding an antigenic protein and with an assistor protein, wherein the assistor protein shares at least one epitope with the antigenic protein, and wherein the nucleic acid and said assistor protein are associated with the same liposomes is described. The composition provides an improved immune response compared to mixtures of liposomes some of which are associated with the nucleic acid and some of which are associated with the assistor protein.
Public/Granted literature
- US20120121690A1 METHOD TO ENHANCE AN IMMUNE RESPONSE OF NUCLEIC ACID VACCINATION Public/Granted day:2012-05-17
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