Invention Grant
- Patent Title: Methods and compositions relating to isocyanate conjugates
- Patent Title (中): 与异氰酸酯共轭物相关的方法和组合物
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Application No.: US12577241Application Date: 2009-10-12
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Publication No.: US08828667B2Publication Date: 2014-09-09
- Inventor: Paul D. Siegel , Tinashe Blessing Ruwona , Donald H. Beezhold , Victor Johnson , Detlef Schmechel
- Applicant: Paul D. Siegel , Tinashe Blessing Ruwona , Donald H. Beezhold , Victor Johnson , Detlef Schmechel
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Gifford, Krass, Sprinkle, Anderson & Citkowski, P.C.
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C07K16/44
Abstract:
Compositions are provided according to embodiments of the present invention which include an isolated antibody or antigen binding antibody fragment characterized by binding specificity for a conjugate which is a reaction product of a protein moiety and an isocyanate moiety. Methods of detecting diisocyanate-protein conjugates in a sample are provided according to embodiments of the present invention which include contacting a sample with one or more isolated antibodies or antigen binding antibody fragments characterized by binding specificity for corresponding diisocyanate-protein conjugate antigens.
Public/Granted literature
- US20100099201A1 METHODS AND COMPOSITIONS RELATING TO ISOCYANATE CONJUGATES Public/Granted day:2010-04-22
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