Invention Grant
US08828949B2 Aprotinin polypeptides for transporting a compound across the blood-brain barrier
有权
用于将化合物转运穿过血脑屏障的抑肽酶多肽
- Patent Title: Aprotinin polypeptides for transporting a compound across the blood-brain barrier
- Patent Title (中): 用于将化合物转运穿过血脑屏障的抑肽酶多肽
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Application No.: US13042017Application Date: 2011-03-07
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Publication No.: US08828949B2Publication Date: 2014-09-09
- Inventor: Richard Beliveau , Michel Demeule , Christian Che , Anthony Regina
- Applicant: Richard Beliveau , Michel Demeule , Christian Che , Anthony Regina
- Applicant Address: CA Montreal
- Assignee: Angiochem, Inc.
- Current Assignee: Angiochem, Inc.
- Current Assignee Address: CA Montreal
- Agency: Duane Morris LLP
- Agent Lee Crews
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K38/16 ; A61K38/22 ; C07K9/00 ; G01N33/53 ; A61K35/30
Abstract:
The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides or conjugates. The present invention also relates to the use of these polypeptides for transporting a compound or drug across the blood-brain barrier of a mammal and in the treatment and diagnosis of neurological diseases.
Public/Granted literature
- US20110171128A1 APROTININ POLYPEPTIDES FOR TRANSPORTING A COMPOUND ACROSS THE BLOOD-BRAIN BARRIER Public/Granted day:2011-07-14
Information query
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