Invention Grant
US08828967B2 Low molecular weight complexes between iron and maltobionic acid, use thereof for intramuscular or subcutaneous administration in the treatment of anemic states, and new pharmaceutical compositions adapted for these uses
有权
铁和麦芽糖二酸之间的低分子量配合物，其用于在治疗贫血状态下用于肌内或皮下施用，以及适用于这些用途的新药物组合物
- Patent Title: Low molecular weight complexes between iron and maltobionic acid, use thereof for intramuscular or subcutaneous administration in the treatment of anemic states, and new pharmaceutical compositions adapted for these uses
- Patent Title (中): 铁和麦芽糖二酸之间的低分子量配合物，其用于在治疗贫血状态下用于肌内或皮下施用，以及适用于这些用途的新药物组合物
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Application No.: US13703111Application Date: 2011-06-08
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Publication No.: US08828967B2Publication Date: 2014-09-09
- Inventor: Michele Autuori , Dario Bosi , Alessandro Lapini Sacchetti , Egidio Marchi
- Applicant: Michele Autuori , Dario Bosi , Alessandro Lapini Sacchetti , Egidio Marchi
- Applicant Address: IT
- Assignee: Biofer S.p.A.
- Current Assignee: Biofer S.p.A.
- Current Assignee Address: IT
- Agency: Cantor Colburn LLP
- Priority: ITMI2010A1028 20100609
- International Application: PCT/EP2011/059498 WO 20110608
- International Announcement: WO2011/154452 WO 20111215
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/715 ; C07H15/04 ; C07H23/00
Abstract:
New low molecular weight complexes between iron and maltobionic acid that can be administered parenterally, preferably intramuscularly or subcutaneously, in the treatment of anemic states, caused by iron deficiencies, and new pharmaceutical compositions adapted for this use. In particular, the invention provides a new complex between preferably trivalent iron and maltobionic acid that is characterized by a molecular weight Mw between 10,000 and 30,000 Da, by a polydispersity of 1.0-1.8 and by an iron content between 25% and 40% by weight.
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