Invention Grant
- Patent Title: Dihydroindolinone derivatives
- Patent Title (中): 二氢吲哚啉酮衍生物
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Application No.: US12994442Application Date: 2009-05-25
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Publication No.: US08829039B2Publication Date: 2014-09-09
- Inventor: Zhedong Yuan , Xiaomin Zhang , Hubo Wang , Xueyan Zhu , Hongjiang Xu , Hui Fu , Wei Song
- Applicant: Zhedong Yuan , Xiaomin Zhang , Hubo Wang , Xueyan Zhu , Hongjiang Xu , Hui Fu , Wei Song
- Applicant Address: CN Shanghai CN Jiangsu
- Assignee: Shanghai Institute of Pharmaceutical Industry,Jiangsu Chiatai Tianqing Pharmaceutical Co., Ltd.
- Current Assignee: Shanghai Institute of Pharmaceutical Industry,Jiangsu Chiatai Tianqing Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Shanghai CN Jiangsu
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: CN2008100098055 20080523
- International Application: PCT/CN2009/071967 WO 20090525
- International Announcement: WO2009/140928 WO 20091126
- Main IPC: A61K31/33
- IPC: A61K31/33 ; C07D209/10 ; C07D403/06

Abstract:
Disclosed are dihydroindolone compounds which can modulate the activity of protein tyrosine kinases, a method for preparing the same, and pharmaceutical compositions comprising the same. Also disclosed are use of such compounds and pharmaceutical compositions thereof in the treatment and/or prophylaxis of protein tyrosine kinase associated diseases in an organism, particularly in the treatment and/or prophylaxis of tumors and fibroblast proliferation associated diseases.
Public/Granted literature
- US20110275671A1 DIHYDROINDOLINONE DERIVATIVES Public/Granted day:2011-11-10
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