Invention Grant
US08829180B2 Method of purifying a low molecular weight hyaluronic acid or cationized hyaluronic acid via precipitation from aqueous solution by addition of alcohol or acetone followed by ph adjustment
有权
通过添加醇或丙酮从水溶液中沉淀后纯化低分子量透明质酸或阳离子化透明质酸的方法，然后进行ph调整
- Patent Title: Method of purifying a low molecular weight hyaluronic acid or cationized hyaluronic acid via precipitation from aqueous solution by addition of alcohol or acetone followed by ph adjustment
- Patent Title (中): 通过添加醇或丙酮从水溶液中沉淀后纯化低分子量透明质酸或阳离子化透明质酸的方法，然后进行ph调整
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Application No.: US13388010Application Date: 2010-12-01
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Publication No.: US08829180B2Publication Date: 2014-09-09
- Inventor: Takushi Yoshida
- Applicant: Takushi Yoshida
- Applicant Address: JP
- Assignee: Kewpie Corporation
- Current Assignee: Kewpie Corporation
- Current Assignee Address: JP
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: JP2009-278259 20091208
- International Application: PCT/JP2010/071437 WO 20101201
- International Announcement: WO2011/070948 WO 20110616
- Main IPC: C08B37/00
- IPC: C08B37/00 ; A61K8/73 ; A61K31/728 ; A23L1/30
Abstract:
Provided a method of producing a purified hyaluronic acid type which comprises adding a water-soluble organic medium to a solution which comprises a hyaluronic acid type having an average molecular weight of 400 to 100,000 and has a pH of 3 or less to obtain a suspension, and adjusting a pH of the suspension in a range of 3.5 to 8 to precipitate a purified hyaluronic acid type.
Public/Granted literature
- US20120130063A1 METHOD OF PRODUCING A PURIFIED HYALURONIC ACID TYPE Public/Granted day:2012-05-24
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