Invention Grant
US08829194B2 Crystalline forms of the sodium salt of (4-{4-[5-(6-trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid
有权
（4- {4- [5-（6-三氟甲基 - 吡啶-3-基氨基） - 吡啶-2-基] - 苯基} - 环己基） - 乙酸的钠盐的结晶形式
![Crystalline forms of the sodium salt of (4-{4-[5-(6-trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid](/docs/US/2014-09-09/US08829194B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline forms of the sodium salt of (4-{4-[5-(6-trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid
- Patent Title (中): （4- {4- [5-（6-三氟甲基 - 吡啶-3-基氨基） - 吡啶-2-基] - 苯基} - 环己基） - 乙酸的钠盐的结晶形式
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Application No.: US13876063Application Date: 2011-10-05
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Publication No.: US08829194B2Publication Date: 2014-09-09
- Inventor: Paul Allen Sutton , Michael J. Girgis , Jessica Liang , Mahavir Prashad , Edwin Bernard Villhauer
- Applicant: Paul Allen Sutton , Michael J. Girgis , Jessica Liang , Mahavir Prashad , Edwin Bernard Villhauer
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Lisa Matovcik
- International Application: PCT/US2011/054841 WO 20111005
- International Announcement: WO2012/047948 WO 20120412
- Main IPC: C07D213/04
- IPC: C07D213/04 ; A61K31/44 ; A61K31/444 ; C07D213/72 ; A61K45/06 ; C07D401/12
![Crystalline forms of the sodium salt of (4-{4-[5-(6-trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid](/abs-image/US/2014/09/09/US08829194B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to novel crystalline forms of (4-{4-[5-(6-Trifluoromethyl-pyridin-3-ylamino)-pyridin-2-yl]-phenyl}-cyclohexyl)-acetic acid, sodium and their use in the treatment or prevention of a condition or a disorder associated with DGAT1 activity in animals, particularly humans. It also relates to processes for making such novel crystalline forms.
Public/Granted literature
- US20130184311A1 CRYSTALLINE FORMS OF THE SODIUM SALT OF (4--CYCLOHEXYL)-ACETIC ACID Public/Granted day:2013-07-18
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