Invention Grant
US08829276B2 Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
有权
通过非哺乳动物糖基转移酶的表达在植物中哺乳动物型糖基化
- Patent Title: Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
- Patent Title (中): 通过非哺乳动物糖基转移酶的表达在植物中哺乳动物型糖基化
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Application No.: US12596063Application Date: 2008-04-17
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Publication No.: US08829276B2Publication Date: 2014-09-09
- Inventor: Gerard Johan Adolph Rouwendal , Dionisius Elisabeth Antonius Florack , Hendrik Jan Bosch
- Applicant: Gerard Johan Adolph Rouwendal , Dionisius Elisabeth Antonius Florack , Hendrik Jan Bosch
- Applicant Address: NL Wageningen
- Assignee: Stichting Dienst Landbouwkundig Onderzoek
- Current Assignee: Stichting Dienst Landbouwkundig Onderzoek
- Current Assignee Address: NL Wageningen
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: EP07106337 20070417
- International Application: PCT/IB2008/000944 WO 20080417
- International Announcement: WO2008/125972 WO 20081023
- Main IPC: C12N15/82
- IPC: C12N15/82 ; A01H5/00 ; C12N9/10 ; C12P21/00
Abstract:
The present invention relates to non-mammalian β-1,4-galactosyltransferases that can be used in their wild-type or in modified forms. The invention further relates to transformed plants and plant cells expressing non-mammalian β-1,4-galactosyltransferase and methods to produce glycoproteins with altered and preferably mammalian-type glycosylation. The invention additionally provides nucleic acid molecules and expression vectors of non-mammalian β-1,4-galactosyltransferases.
Public/Granted literature
- US20120210466A9 MAMMALIAN-TYPE GLYCOSYLATION IN PLANTS BY EXPRESSION OF NON-MAMMALIAN GLYCOSYLTRANSFERASES Public/Granted day:2012-08-16
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