Seismic imaging systems and methods that employ sensitivity kernel-based migration velocity analysis in 3D anisotropic media may demonstrate increased stability and accuracy. Survey data analysts employing the disclosed systems and methods are expected to provide better images of the subsurface and be better able to identify reservoirs and deposits for commercial exploitation. Certain embodiments migrate seismic survey data with an anisotropic velocity model to obtain common angle image gathers. These gathers are processed to obtain depth residuals along one or more horizons. Angle-domain sensitivity kernels are used to convert the depth residuals into velocity errors, which are then used to refine the velocity model. A user is then able to view a representation of the subsurface structure determined in part from the refined velocity model. Multiple iterations may be needed for the velocity model to converge. The velocity model may be a layered to have constant velocity values between formation boundaries.