A method of controlling driving of the pop-up tweeter speaker which includes (a) determining whether or not an opening of the tweeter speaker is normally completed and popping-down the tweeter speaker if it is determined that the opening is not normally completed, while popping-up the tweeter speaker based on a speaker control condition under an ON condition of an accessory (ACC) condition, (b) determining whether or not a close of the tweeter speaker is normally completed and popping-up the tweeter speaker if it is determined that the close is not normally completed, while popping-down the tweeter speaker based on an OFF condition of one of the speaker control condition and the ACC condition, and (c) maintaining a position state of the tweeter speaker until the speaker control condition or the ACC condition becomes an OFF condition when popping-down the tweeter speaker in (a) or popping-up the tweeter speaker in (b).