Invention Grant
US08834900B2 Combination motif immune stimulatory oligonucleotides with improved activity
有权
具有改善活性的组合基序免疫刺激性寡核苷酸
- Patent Title: Combination motif immune stimulatory oligonucleotides with improved activity
- Patent Title (中): 具有改善活性的组合基序免疫刺激性寡核苷酸
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Application No.: US10224523Application Date: 2002-08-19
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Publication No.: US08834900B2Publication Date: 2014-09-16
- Inventor: Arthur M. Krieg , Jorg Vollmer
- Applicant: Arthur M. Krieg , Jorg Vollmer
- Applicant Address: US IA Iowa City DE Düsseldorf
- Assignee: University of Iowa Research Foundation,Coley Pharmaceutical GmbH
- Current Assignee: University of Iowa Research Foundation,Coley Pharmaceutical GmbH
- Current Assignee Address: US IA Iowa City DE Düsseldorf
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K45/00
- IPC: A61K45/00 ; C07H21/02
Abstract:
A class of immunostimulatory nucleic acids having at least two functionally and structurally defined domains is provided. This class of combination motif immunostimulatory nucleic acids activates an immune response and is useful for treating a variety of immune related disorders such as cancer, infectious disease, and allergic disorders. The nucleic acids also stimulate activation of natural killer cells and production of type 1 interferon.
Public/Granted literature
- US20030148976A1 Combination motif immune stimulatory oligonucleotides with improved activity Public/Granted day:2003-08-07
Information query
