Invention Grant
- Patent Title: Methods of analysis of allelic imbalance
- Patent Title (中): 等位基因不平衡分析方法
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Application No.: US13667998Application Date: 2012-11-02
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Publication No.: US08835116B2Publication Date: 2014-09-16
- Inventor: Giulia Kennedy
- Applicant: Affymetrix, Inc.
- Applicant Address: US CA Santa Clara
- Assignee: Affymetrix, Inc.
- Current Assignee: Affymetrix, Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: Banner & Witcoff, Ltd.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12Q1/68 ; C12N15/10

Abstract:
Methods are provided for identification of genes that are imprinted. In another embodiment methods are provided for identification and analysis of genes whose expression shows allelic imbalance. The expression products transcribed from genes that are present in the genome as two or more alleles may be distinguished by hybridization to an array designed to interrogate individual alleles. Genes whose transcription products are present in amounts that vary from expected are candidates for allelic imbalance, imprinting and imprinting errors.
Public/Granted literature
- US20130190199A1 Methods of Analysis of Allelic Imbalance Public/Granted day:2013-07-25
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