Invention Grant
- Patent Title: Modular functional peptides for delivery of nanoparticles
- Patent Title (中): 用于递送纳米颗粒的模块化功能性肽
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Application No.: US13621880Application Date: 2012-09-18
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Publication No.: US08835172B2Publication Date: 2014-09-16
- Inventor: James B. Delehanty , Igor L. Medintz , Hedi M. Mattoussi , Jeffrey R. Deschamps , Glyn Dawson , Philip E. Dawson , Juan Bautista Blanco-Canosa , Kelly Boeneman
- Applicant: James B. Delehanty , Igor L. Medintz , Hedi M. Mattoussi , Jeffrey R. Deschamps , Glyn Dawson , Philip E. Dawson , Juan Bautista Blanco-Canosa , Kelly Boeneman
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary of the Navy
- Current Assignee: The United States of America, as represented by the Secretary of the Navy
- Current Assignee Address: US DC Washington
- Agency: US Naval Research Laboratory
- Agent Roy Roberts
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; A61K38/00 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00 ; C07K17/00 ; A61K49/00 ; G01N33/58 ; C07K17/14 ; B82Y5/00

Abstract:
A peptide directs nanoparticles (such as quantum dots) to the plasma membrane of mammalian cells. A method of delivery of a nanoparticle to a plasma membrane of a cell includes providing to the cell a nanoparticle attached to a peptide configured to direct the nanoparticle the plasma membrane, and allowing the cell to take up the nanoparticle. The nanoparticle can be a FRET donor to an organic dye.
Public/Granted literature
- US20130130296A1 Modular Functional Peptides for Delivery of Nanoparticles Public/Granted day:2013-05-23
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