Invention Grant
US08835387B2 Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
有权
用于治疗自身免疫性和炎性疾病的组氨酰-tRNA合成酶
- Patent Title: Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
- Patent Title (中): 用于治疗自身免疫性和炎性疾病的组氨酰-tRNA合成酶
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Application No.: US13769100Application Date: 2013-02-15
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Publication No.: US08835387B2Publication Date: 2014-09-16
- Inventor: Kyle P. Chiang , Elisabeth Gardiner , Ching-Fun Lau , Wing-Sze Lo , Jeffrey Greve , Melissa Ashlock , John D. Mendlein
- Applicant: aTyr Pharma, Inc. , Pangu BioPharma Limited
- Applicant Address: US CA San Diego CN Hong Kong
- Assignee: aTyr Pharma, Inc.,Pangu Biopharma Limited
- Current Assignee: aTyr Pharma, Inc.,Pangu Biopharma Limited
- Current Assignee Address: US CA San Diego CN Hong Kong
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K1/00 ; A61K38/17 ; C12N9/00 ; A61K38/16 ; A61K48/00
Abstract:
The present invention relates generally to compositions and methods comprising histidyl-tRNA synthetase polypeptides or other specific blocking agents for the treatment autoimmune diseases and other inflammatory diseases, including those related to Jo-1 antibodies.
Public/Granted literature
- US20130344096A1 HISTIDYL-TRNA SYNTHETASES FOR TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES Public/Granted day:2013-12-26
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