Invention Grant
- Patent Title: RNA molecules that upregulate insulin production
- Patent Title (中): 上调胰岛素生产的RNA分子
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Application No.: US13877991Application Date: 2011-10-10
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Publication No.: US08835400B2Publication Date: 2014-09-16
- Inventor: Pal Saetrom
- Applicant: Pal Saetrom
- Applicant Address: GB London
- Assignee: Mina Therapeutics Limited
- Current Assignee: Mina Therapeutics Limited
- Current Assignee Address: GB London
- Agency: DT Ward, PC
- Agent Donna T. Ward; Hang Zhu
- Priority: GB1016989.4 20101008; GB1103745.4 20101008
- International Application: PCT/GB2011/051940 WO 20111010
- International Announcement: WO2012/046084 WO 20120412
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C12Q1/68 ; C12N15/113 ; C12N15/11
Abstract:
The present invention provides a short RNA capable of upregulating MafA expression in a human cell, wherein the short RNA includes a first strand which is 19 to 25 nucleotides in length and comprises the sequence AUCUGUACUGGAUGAGCGG (SEQ ID NO:1) or UUUCCCGCAGGAGAUUGAC (SEQ ID NO:2). Also provided are uses of the short RNA, particular medical uses, and induced cells and uses of the induced cells.
Public/Granted literature
- US20130323211A1 SHORT RNA MOLECULES Public/Granted day:2013-12-05
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