Invention Grant
US08835429B2 Pyrimidine compounds, their use as mTOR kinase and Pl3 kinase inhibitors, and their syntheses
有权
嘧啶化合物,它们作为mTOR激酶和Pl3激酶抑制剂的用途及其合成
- Patent Title: Pyrimidine compounds, their use as mTOR kinase and Pl3 kinase inhibitors, and their syntheses
- Patent Title (中): 嘧啶化合物,它们作为mTOR激酶和Pl3激酶抑制剂的用途及其合成
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Application No.: US13264776Application Date: 2010-04-15
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Publication No.: US08835429B2Publication Date: 2014-09-16
- Inventor: Kevin Joseph Curran , Joshua Aaron Kaplan , David James Richard , Jeroen Cunera Verheijen , Arie Zask
- Applicant: Kevin Joseph Curran , Joshua Aaron Kaplan , David James Richard , Jeroen Cunera Verheijen , Arie Zask
- Applicant Address: US NY New York
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NY New York
- Agent David Rubin
- International Application: PCT/US2010/031191 WO 20100415
- International Announcement: WO2010/120998 WO 20101021
- Main IPC: C07D498/08
- IPC: C07D498/08 ; A61K31/5386

Abstract:
The invention relates to pyrimidine compounds of the Formula I: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
Public/Granted literature
- US20120134959A1 PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES Public/Granted day:2012-05-31
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