Invention Grant
- Patent Title: 2,4-pyrimidinediamine compounds and their uses
- Patent Title (中): 2,4-嘧啶二胺化合物及其用途
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Application No.: US14038521Application Date: 2013-09-26
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Publication No.: US08835430B2Publication Date: 2014-09-16
- Inventor: Rajinder Singh , Ankush Argade , Donald Payan , Susan Molineaux , Sacha Holland , Jeffrey Clough , Holger Keim , Somasekhar Bhamidipati , Catherine Sylvain , Hui Li , Alexander Rossi
- Applicant: Rajinder Singh , Ankush Argade , Donald Payan , Susan Molineaux , Sacha Holland , Jeffrey Clough , Holger Keim , Somasekhar Bhamidipati , Catherine Sylvain , Hui Li , Alexander Rossi
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Agent Travis Young
- Main IPC: C07D239/48
- IPC: C07D239/48 ; C07D403/12 ; C07D413/12 ; A61K31/506 ; A61K31/538 ; A61K31/505 ; A61K31/551 ; A61K31/5383 ; C07D405/12 ; C07D405/14 ; C07D409/12 ; C07D401/12 ; C07D409/14 ; A61K31/5377 ; C07D413/14 ; A61K31/519 ; C07D413/10 ; C07D403/14 ; C07D265/36 ; C07D417/14 ; A61K45/06 ; C07D498/04 ; C07D401/14 ; C07D417/12
Abstract:
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.
Public/Granted literature
- US20140031350A1 2,4-Pyrimidinediamine Compounds and Their Uses Public/Granted day:2014-01-30
Information query
