Invention Grant
US08835440B2 Cyclic pyrimidin-4-carboxamides as CCR2 receptor antagonists for treatment of inflammation, asthma and COPD
有权
循环嘧啶-4-甲酰胺作为治疗炎症，哮喘和COPD的CCR2受体拮抗剂
- Patent Title: Cyclic pyrimidin-4-carboxamides as CCR2 receptor antagonists for treatment of inflammation, asthma and COPD
- Patent Title (中): 循环嘧啶-4-甲酰胺作为治疗炎症，哮喘和COPD的CCR2受体拮抗剂
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Application No.: US13949696Application Date: 2013-07-24
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Publication No.: US08835440B2Publication Date: 2014-09-16
- Inventor: Heiner Ebel , Sara Frattini , Riccardo Giovannini , Christoph Hoenke , Thomas Trieselmann , Patrick Tielmann , Stefan Scheuerer , Silke Hobbie , Frank Buettner
- Applicant: Heiner Ebel , Sara Frattini , Riccardo Giovannini , Christoph Hoenke , Thomas Trieselmann , Patrick Tielmann , Stefan Scheuerer , Silke Hobbie , Frank Buettner
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Edward S. Lazer
- Priority: EP08172336 20081219; EP09160416 20090515
- Main IPC: A01N43/54
- IPC: A01N43/54 ; C07D239/42 ; C07D401/04 ; C07D498/10 ; C07D403/06 ; A61K31/55 ; C07D491/052 ; C07D401/06 ; A61K31/553 ; C07D405/14 ; C07D471/10 ; C07D407/14 ; C07D417/14 ; A61K31/5377 ; A61K31/551 ; C07D471/04 ; C07D403/14 ; C07D451/02 ; C07D401/14 ; A61K31/506 ; C07D413/14
Abstract:
The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.
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Information query
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