Invention Grant
- Patent Title: Mandelamide heterocyclic compounds
- Patent Title (中): 曼德拉酰胺杂环化合物
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Application No.: US13642755Application Date: 2011-04-21
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Publication No.: US08835470B2Publication Date: 2014-09-16
- Inventor: Robert J. Cherney , Yanlei Zhang
- Applicant: Robert J. Cherney , Yanlei Zhang
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Gary D. Greenblatt
- International Application: PCT/US2011/033364 WO 20110421
- International Announcement: WO2011/133734 WO 20111027
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/497 ; A61K31/4439 ; A61K31/427 ; A61K31/4245 ; C07D417/14 ; C07D413/14 ; C07D413/04

Abstract:
Disclosed are compounds of Formula (I) or stereoisomers, salts, or prodrugs thereof, wherein: Q is, or R1 is phenyl substituted with zero to 3 substituents; and R1, R2, R3, R4, R5, and G are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
Public/Granted literature
- US20130045964A1 MANDELAMIDE HETEROCYCLIC COMPOUNDS Public/Granted day:2013-02-21
Information query
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